Im desperate Matlab - VISA- Siglent

Hello everybody,
i have this problem: trying to upload arbitrary waveform into SDG6022x, but i just cant figure out the data format, anyone who could help me with that ? its 16bit 2's complement, 

but signed integers doesnt work, 
unsigned integers doesnt work,
if i devide data into 2 bytes it still doesnt work 
or im doing something wrong ...